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What is Diazepam?
Diazepam (brand name: Valium) is a psychoactive drug which acts on the central nervous system. It is a great oral treatment that belongs to the medicine type benzodiazepine family, the identical family which contains flurazepam (dalmane), lorazepam (Ativan), alprazolam (Xanax), clonazepam (Klonopin) as well as some others. The medication is accepted and authorized in November 1963 and anyone can buy diazepam with doctor’s prescription after this date.
What is Diazepam used for?
The drug is widely prescribed to relieve anxiety, general anxiety disorder, agitation, body shakeups, seizures, and insomnia. Diazepam is also recommended to relieve the alcohol and benzodiazepine withdrawal symptoms.
This medication actively affects the neuron function by inhibit their excitability. The increased excitability is a result of neurochemical imbalances in the brain. These chemicals control the neuron activity in certain part of central nervous system. When the balance is disturbed the neuron either increases or slows down. Increased neuron activity results in anxiety and agitation whiled a slowed down activity results in insomnia. Diazepam relieves these symptoms by re-establishing the balance in the levels of these neurochemicals.
Why is Diazepam prescribed?
Also, in addition to being excellent for anxiety, Valium is generally utilized as a good muscles relaxant and for sleeping troubles. In certain cases, it is also useful to treat seizures in several sufferers with epilepsy. It is considered as a long-lasting benzodiazepine, in which people need a single dosage to continue throughout the day. Valium is commonly given to individuals with general anxiety problems; however, it is also prescribed for the following conditions:
Many individuals feel anxiousness prior to a significant occasion. Anxiety is the illnesses that load people’s lives with mind-boggling anxiousness fear that happen to be continual and unremitting, and which will grow progressively worse. Valium is authorized as a nervous (anxiety) remedy. However, Valium just isn’t for “everyday anxiety” and it is suggested only for short-term use. Other anxiousness drugs (for example SSRIs, a particular form of antidepressants) are far more suitable for long-term use.
Stopping alcohol instantly isn’t always a great plan. In reality, it could be quite risky and might be life-threatening. It should always be performed under the supervision of a healthcare professional, and hospitalization is usually needed. Folks who drink heavily or regularly may suffer from alcohol withdrawal signs and symptoms, when they end consuming alcohol too quickly. Mild alcohol withdrawal signs can consist of depression, nervousness, slight shakiness, clammy skin or alcohol cravings. Valium may help with delirium tremens, shakiness and agitation connected with alcohol withdrawal.
Involuntary contraction of the muscle or a group of muscles is called muscle spasms. Though not commonly harmful, muscle spasms can be uncomfortable and unpleasant. Valium is valuable for treating muscle spasms because of the following causes: joint or muscle inflammation, Stiff-man syndrome (a rare neurological disorder), cerebral palsy, injury, Athetosis (a movement disorder of the hands and feet) and Paraplegia.
How does Diazepam work?
It works by lowering the results of GABA (gamma-aminobutyric acid) in the human brain. Gamma Aminobutyric Acid (GABA) is a neurotransmitter (a chemical which is utilized by nerve cells to communicate with each other) which inhibits activity within the actual brain. It is considered that too much action in the brain may result to anxiety or other psychiatric disorders and diazepam basically slows down excessive activity inside the brain.
What are the Diazepam side effects?
One of the more important diazepam side effects is that it slows down your brain’s activity which can influence your judgment, thinking, and motoric skills. Therefore, it is not recommended you drive, operate machinery, or do other tasks that ask for your alertness. This is just one important additional side effects if which you should be aware of.
Common side effects of diazepam:
- Tiredness or fatigue
- Shakiness and unsteady walk
- Weak muscles and the inability to control them
- Dry mouth or excessive saliva
Most of the diazepam side effects do not need medical attention. Most likely they will go away during treatment as your body adjusts to the medicine. However, if they continue or are bothersome you might want to contact your healthcare provider.
What is the proper Diazepam dosage?
This benzodiazepine is an extremely typical drug that has been constantly used to treat anxiety or seizures. Depending on the type of symptoms and circumstances that the patient is in, there are many different types of health providers that will prescribe different Diazepam dosages in order to help treat the conditions displayed.
Still, the medical board has given a recommended dosage and those that are on the medication should consider whether or not they are taking the recommended dosage and whether they are overdosing on the drug. This medicine can be used to treat both adults and children depending on the conditions that are experienced.
Generally speaking, the recommended diazepam dosage for healthy adults ranges from around 6 – 40 mg depending on the type of conditions that the adult displays. It also depends on the type of discomforts that they claim to have.
Those that are taking it for alcohol withdrawal will find that they are generally prescribed anywhere from 30 – 40 mg a day. Elderly people will generally be recommended a smaller dosage of around 4 – 10 mg, and children will generally have it in the same dosage range as the elderly even if they are not built the same as an adult and do not have the same body mass. This is due to the fact that children are generally more susceptible to the drug.
The different types of recommended diazepam dosage will highly depend on the person who is recommending the drug and the person who is taking the drug. Depending on the advice that is given by the health provider, different people may be taking different dosages despite having the same type of symptoms.
It highly depends on the type of symptoms experienced, the age of the patient, the body mass of the patient, and the type of condition that the drug is being used to treat.
How long does Diazepam take to work?
The answer on the question “how long does diazepam take to work?” is: it depends. The time for diazepam to kick in depends on how and what you’re taking it for. It can be taken by mouth, injection, or rectal gel.
- When administered via injection, it needs only 5 minutes to show its effects.
- When taken as a pill or tablet for anxiety, the effects kick in 15 to 60 minutes after ingestion. However, it may take 2 weeks to feel its full effects.
- Rectal gel may be used for patients who have seizures. The effects should be noticed quickly after administration.
How long does Diazepam last?
If you’ve just taken this benzodiazepine, then you might wonder how “how long does diazepam last?”. The amount of time any medicine stays active in your body has to do with the half life of it. The larger the dose and the more frequently you take it, the higher the half life.
The diazepam half life is 30 to 56 hours. This means its effects will stay active somewhere between that timeframe. However, based on the half life it’ll take around 3 weeks for all of the metabolites to be completely removed from the body.
There are many variables that can influence how long this drug stays visible in your system. It depends on your metabolism, age, weight, and percentage of body fat. If you exercise a lot and drink high volumes of water it can help your body to eliminate the metabolites.
With which other medicines can Diazepam interact?
There are many different types of interactions that other drugs would have with this benzodiazepine and it is important to consult a physician or a health provider when being put on it. Have all of the information regarding other drugs available just in case.
This medicine is prescribed for the treatment of anxiety, muscle tremor, seizures and indication of alcohol withdrawal. Drug interactions with Valium include narcotics, omeprazole (Prilosec), barbiturates, fluvoxamine (Luvox), itraconazole (Sporanox), ketoconazole (Nizoral), alcohol, cimetidine (Tagamet) and fluoxetine (Prozac). So, these medicines should be avoided when you are getting treated with Valium.
Generally speaking, antibiotics, alcohol and other drugs used to treat mental disorders should not be taken in conjunction with diazepam due to the possible consequences.
Mixing diazepam and alcohol can be very dangerous and lead to overdose. As well diazepam and alcohol depress the central nervous system. Therefore, mixing them together can be unpleasant and even life threatening. After experiencing nausea, breathing can slow down this much that it can even lead to death.
When shouldn’t I take Diazepam?
Valium should be avoided at the following cases:
- When you take other medicines that can interact with Valium
- When you are pregnant. Foetal irregularities or abnormalities can have effects on an unborn baby.
- When you are breast feeding. The effect of Valium can be excreted into the breast milk and can have an effect on the nursing toddler. For this reason, it should be avoided by women who are nursing.
Is Diazepam addictive?
Benzodiazepines are notorious for developing a tolerance and physical dependence on the drugs. This medicine and other benzodiazepines are the most commonly prescribed drugs in the United Kingdom for anxiety. It has been clinically proven that if the drugs are used for longer period, there is very good chance that the patient develops dependency on the drug. Withdrawal after a long-term usage will give rise to the withdrawal symptoms – a spectrum of clinical disorders observed in the users after its abandonment. The withdrawal symptoms of diazepam are quite similar to that of alcohols. Dependency can occur even after the short-term usage of standard dosages of the drug; however, long-term usage of greater dosages will result in more severe and unpleasant withdrawal symptoms.
How does Diazepam withdrawal happen?
Extensive research and studies have been carried out to study the medical after-effects of the drug when the usage is stopped. The reaction of the drug and physical dependence of the human body was first observed by Hollister and his collaborators in 1963 while they were studying the treatment of schizophrenic patients with diazepam. It has also been studied that the patients who stop using the medicine often confuse their withdrawal symptoms with their disorders and think that their previous symptoms are returning and hence resume the drug usage.
The most authentic and solid study of the withdrawal symptoms was carried out by Winokur and his helpers.
The medical literature on the diazepam withdrawal symptoms suggests that the symptoms occur after 1-11 days of the withdrawal. The symptoms, according to the literature, include psychosis, anxiety and agitation, motor dysfunction, seizures, and restlessness. A wide spectrum of symptoms was observed. The literature indicates that some patients developed some of the symptoms while others were diagnosed with the whole spectrum of symptoms. The spectrum included symptoms like disturbed sleep, insomnia, anxiety, depression, hysterical neurosis, cardiac neurosis, backache, headache, and hyperventilation – even Tetanus.
Medical advisors suggest a scheduled, gradual withdrawal of the drug with small reductions in the dosages to avoid the symptoms above.
Where can I buy Diazepam?
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